Since the early part of the 1990’s, Karo Bio has specialized in nuclear receptor based drug discovery. These receptors control gene activity and are important targets for treatment of a number of diseases. In this field, Karo Bio has generated innovative treatment concepts and first in class compounds on the basis of scientific and technological leadership. In recent years, Karo Bio has established preclinical and clinical development resources and is capable of bringing compounds through clinical phase II development before partnering.