Custom CRISPR Gene Editing Services for Research
Karobio provides custom CRISPR/Cas9 gene editing services for academic and biotechnology research. Our expertise includes gene knockouts, knock-ins, base editing, RNA interference (RNAi), and targeted mutation design for functional genomics, disease modeling, and pathway analysis. We support mammalian cells, stem cells, plant systems, and microbial models with precision-engineered editing workflows.
Our Services
CRISPR/Cas9 Gene Knockout Services
Targeted gene disruption with validated sgRNA design and minimal off-target activity.
Gene Knock-In & HDR Editing
Precise insertion of reporter genes, tags, or mutations using homology-directed repair (HDR).
Base Editing & Targeted Mutagenesis
Single-nucleotide modifications without double-strand breaks.
RNA Interference (RNAi) Solutions
Transient or stable gene silencing strategies.
Disease Model Development
Custom cell line engineering for oncology, immunology, and genetic disorder research.
CRISPR/Cas9 Gene Editing & Knockout Services
CRISPR/Cas9 gene knockouts, knock-ins, base editing, and RNA interference (RNAi) for functional genomics and disease model development.
Custom Cell-Based Assays & Functional Screening
Tailored cellular assays for signaling pathways, gene expression analysis, drug screening, and mechanism-of-action studies.
Recombinant Protein Expression & Purification Services
High-yield expression of recombinant proteins, cytokines, enzymes, and antibodies in mammalian, bacterial, or yeast systems.
Single-Cell RNA Sequencing (scRNA-seq) Services
Advanced single-cell transcriptomics for studying gene expression patterns, cell differentiation, and cellular heterogeneity.
Personalized Cellular Assays
Tailored to Your Research Needs
At Karobio, we offer customized cellular assays designed to support your specific research objectives. Whether you are studying cell signaling pathways, gene expression dynamics, or drug response mechanisms, we provide tailored assay platforms for mammalian cell lines, primary cells, and induced pluripotent stem cells (iPSCs).
- Custom Assay Development: Tailored assay design for specific cell types, genes, and experimental conditions.
- High Sensitivity: Precise and reproducible measurements with minimized background interference.
- Flexible Platforms: Suitable for high-content screening, phenotypic analysis, and cell viability assays.
- Rapid Results: Streamlined workflows delivering reliable and timely experimental data.
Custom Protein Expression Systems
Optimized for Your Research
We provide custom protein expression systems for the production of recombinant proteins, enzymes, and research-grade antibodies. Each workflow is optimized to support expression efficiency, correct folding, and functional performance tailored to your experimental requirements.
- Custom Expression Systems: Tailored protocols for bacterial, yeast, mammalian, and insect cell expression platforms.
- High Yields: Optimized expression conditions for enhanced protein production and stability.
- Purification Support: Scalable purification and isolation strategies ensuring high purity and activity.
- Custom Antibody Development Services: End-to-end antibody generation designed for specificity, reproducibility, and reliable research performance.
Custom Single-Cell RNA Sequencing (scRNA-seq) Services
We provide custom single-cell RNA sequencing (scRNA-seq) services designed to deliver high-resolution insights into individual cell populations. Whether you are studying gene expression patterns, somatic mutations, or cellular heterogeneity, we tailor sequencing workflows to meet your specific research objectives.
Tailored Sequencing Strategies
Custom-designed single-cell sequencing protocols targeting rare cell populations, lineage tracing studies, and specific genetic markers to align with your research focus.
High Sensitivity
In-depth analysis of gene expression, transcriptomic variation, and cellular diversity at single-cell resolution with minimized technical noise.
Flexible Platforms
Support for diverse applications including developmental biology, immune profiling, tumor microenvironment analysis, and disease modeling studies.
Efficient Workflow
Streamlined sequencing pipelines from sample preparation to bioinformatic analysis, ensuring accurate and timely data delivery.
Our Leadership
Meet Our Biotechnology Team
Our experts are dedicated to advancing the frontiers of biotechnology. Get to know the visionary leaders driving innovative research and transformative solutions.
Lieven Gevaert
Bio Engineer & CEO, Gentaur Genprice
Lieven is a seasoned biotechnology engineer and visionary leader. As Owner and CEO of Gentaur Genprice since 2000 and a ResearchGate author, he drives innovative breakthroughs in biotech.
Djoumana Ounas
Pharmacist & Assistant Professor, Analytical Chemistry
Djoumana offers deep expertise in pharmaceutical sciences and regulatory support. Her consultative approach and academic insight empower advanced research in analytical chemistry.
Vasiliy D. Abaev
PhD in Biotechnology & Biomolecules, Sales & Marketing Director
Vasiliy holds a PhD in Biotechnology and Biomolecules. He leads sales and marketing initiatives while providing technical and scientific support to foster growth in the biotech sector.
Latest Updates
Karobio Insights
Explore the latest trends, tips, and best practices in modern biotechnology. From gene editing breakthroughs to innovative biomanufacturing techniques, stay ahead with insights from industry experts.
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What is Draxin?
Draxin, also written as DRAXIN, is a protein-coding gene product known as dorsal inhibitory axon guidance protein. In neuroscience, Draxin is mainly studied as a secreted extracellular guidance cue that influences how growing axons navigate during nervous system development. In humans, UniProt descr...
Understanding qPCR Variability
qPCR inconsistency typically appears as:High variation between replicatesUnexpected Ct valuesLow amplification efficiencyNon-specific amplificationThese issues usually originate from sample quality, experimental setup, or reagent performance.
What is Tumor Necrosis Factor α (TNF-α)?
Tumor Necrosis Factor α (TNF-α) is a potent cytokine primarily produced by macrophages and other immune cells (Wikipedia).It plays a critical role in regulating immune responses, inflammation, and the apoptosis (cell death) of tumor cells. Elevated levels of TNF-α are often associated with chronic i...
Contact Us
Get in Touch
We're here to help—reach out with any questions about our biotechnology products or services.
Have a question or need help? Drop us an email, and we'll respond within 24 hours.
Phone
Prefer to chat? Give us a call Monday–Friday, 9 AM–5 PM (CET).
Worldwide Presence
Visit our headquarters at Voortstraat 49, 1910 Kampenhout, Belgium. We proudly serve customers and research institutions across the globe through our international offices.